Abstract Metzler: Anomalous diffusion in membranes and cytoplams of biological cells
A surging amount of experimental and simulations studies reveals persistent
anomalous diffusion in both cellular membranes and the cytoplasm [1,2]. The
anomalous diffusion is observed for micron-sized objects down to labelled
single molecules such as green fluorescent proteins .
This talk will first present results from large scale computer simulations
and stochastic analysis of the motion of lipids and embedded proteins in
lipid bilayer model membranes , indicating that increased disorder leads
to longer and longer lasting anomalous diffusion. In particular, the motion
of lipids and proteins can become non-Gaussian . In the membranes of living
cells anomalous diffusion of embedded protein channels can last over several
hundreds of seconds . In particular, this anomalous diffusion can become
non-ergodic and exhibit ageing, two topics explained and discussed in this
The findings of anomalous diffusion in membranes will be complemented by a
brief summary of anomalous diffusion in the cellular cytoplasm, referring to
both subdiffusion of passive tracers and superdiffusion due to active
motion in cells.
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