Population Optimum Design of Experiments PODE 2015 Isaac Newton Institute for Mathematical Sciences, Cambridge 7 July 2015
9.30 - 10.00	Registration
10.00 - 10.05	Welcome
10.05 - 11.00	France Mentre, INSERM, Paris 10 years of progress in population design methodology and applications (slides).
	Sergei Leonov, Tobias Mielke, ICON Clinical Research Optimal design and parameter estimation for population PK/PD models (slides).
11.00 - 11.30	Tea/Coffee
11.30 - 12.30	Marie-Karelle Riviere, INSERM, Paris Evaluation of the Fisher information matrix in nonlinear mixed effects models using Monte Carlo Markov Chains (slides).
	Sebastian Ueckert, INSERM, Paris Computation of the Fisher information matrix for discrete nonlinear mixed effects models.
12.30 - 14.00	Lunch
14.00 - 15.30	Tim Waite, University of Southampton Design for generalized linear models with random block effects (slides).
	Steve Gilmour, University of Southampton Design and analysis of in-vitro pharmacokinetic experiments (slides).
	Moreno Ursino, INSERM, Paris Incorporating pharmacokinetic information in phase I studies in small populations (slides).
15.30 - 16.00	TEA/COFFEE
16.00 - 17.00
	Andy Hooker, Uppsala University Model based adaptive optimal designs of adult to children bridging studies using FDA proposed stopping criteria (slides).
	Valerii Fedorov, Innovation Center, ICON plc. Cost constrained optimal design for regression models with random parameters (slides).
17.00 - 17.30	Discussion
~ PODE ~