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PODE 2010 Population Optimum Design of Experiments:
Workshop Bayer Schering Pharma AG, 11/12
June 2010 |
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Friday, 11 June 14:15-14:30 |
Welcome |
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Session 1 |
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14.30 - 15.00 |
Approximations of the population Fisher information
matrix - differences and consequences (slides) Joakim Nyberg, Sebastian Ueckert and Andrew C. Hooker Department of Pharmaceutical Biosciences, |
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15.00 - 15.30 |
Optimization of sampling times for PK/PD models:
approximation of elemental Fisher information matrix (slides) Valerii V. Fedorov, Sergei L. Leonov GlaxoSmithKline, |
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15.30 - 16.00 |
Application of Quasi-Newton Algorithms in Optimal
Design (slides) Sebastian Ueckert, Joakim Nyberg and Andrew C.
Hooker Department
of Pharmaceutical Biosciences, |
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16.00 - 16.30 |
Coffee break |
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Session 2 |
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16.30 - 17.00 |
Optimal design and
QT-prolongation detection in oncology studies (slides) Sylvain
Fouiliard, Marylore Chenel Department of Clinical Pharmacokinetics, Institut de
Recherches Internationales Servier, France |
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17.00 - 17.30 |
Design evaluation and
optimisation in crossover pharmacokinetic studies analyzed by nonlinear mixed
effects models (slides) Thu
Thuy Nguyen, Caroline Bazzoli, France Mentre UMR738
INSERM and University |
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17.30 - 18.00 |
D-optimal Adaptive Bridging
Studies in Pharmacokinetics (slides) Lee-Kien Foo, Stephen Duffull |
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Saturday, 12 June |
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Session 3 |
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9.30 - 10.00 |
Design Evaluation and Optimization
for models of Hepatitis C viral dynamics (slides) J. Guedj (1), C.
Bazzoli (2), A.U. Neumann (3), F. Mentre (2) (1)Los Alamos
National |
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10.00 - 10.30 |
Noninferiority
trial designs for odds ratios and risk differences (slides) Joan F.
Hilton |
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10.30 - 11.00 |
Optimum designs
for nonlinear mixed effects model in the presence of covariates (slides) Barbara
Bogacka Queen Mary, |
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11.00 - 12.00 |
General Discussion, future meetings |
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~ PODE ~ |
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