PODE 2008 Population Optimum Design of Experiments: Workshop University Paris Diderot, France June 23^rd, 2008
9.00-9.15	Welcome
Session 1: Statistical Developments and Optimisation algorithm Chair: Steve Dufful
9.15 - 9.45	Rainer Schwabe: General considerations about designs for mixed models illustrated by very simple examples and potential implications to PPK designs. (slides)
9.45 - 10.15	Joakim Nyberg: Different approximations and methods for calculating the FIM and their consequences. (slides)
10.15 - 10.45	Bruno Boulanger, Jonathan Jaeger, Astrid Jullion: BAST: Development of a Bayesian adaptive sampling time strategy for PK studies. (slides)
10.45 - 11.15	Break
Chair: Basia Bogacka
11.15 - 11.45	Kay Ogungbenro: An effective approach for obtaining optimal sampling windows for population pharmacokinetic experiments. (slides)
11.45 - 12.15	Steve Dufful: Highly accurate and rapid solutions for models defined as ODEs.
12.15 - 13.15	Lunch
Session 2: Application of optimal design in drug development and academia Chair: Leon Aarons
13.15 - 13.45	Sergei Leonov: Optimization of sampling times for a combined PK/PD model: optimal design as a reference point. (slides)
13.45 - 14.15	Marylore Chenel: Drug drug interaction predictions with PBPK and optimal sampling design. (slides)
14.15 - 14.45	Andy Hooker: Two applications (glucose-insulin and disease-progression) and the methods that we needed to use to compute these designs. (slides)
14.45 - 15.00	Break
15.00 - 15.30	Caroline Bazzoli, Sylvie Retout, Emmanuelle Comets & France Mentre: Optimal design with cost functions for the pharmacokinetics of AZT and AZT-TP. (slides)
15.30 - 16.00	Mats Karlsson: A search for an ethically attractive dose-finding design for a drug with expected narrow therapeutic interval. (slides)
Session 3: Discussion on Software Chair: France Mentre
16.00 - 17.00	All authors of software: discussion on the updating of Page 2007 table with software specifications. All: Discussion on the need to organize software evaluation for PODE09
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