PODE 2007 Population Optimum Design of Experiments: Workshop Pfizer, 4th of May 2007 |
|
9.30 - 10.00 |
Welcome Tea/coffee |
Tutorial 10.00
- 11.00 |
R.
Schwabe (Otto von Guericke University
Magdeburg) The equivalence theorem in optimal design (abstract, slides) |
11.00 - 11.30 |
Tea/coffee |
Theory and Methods 11.30 - 12.00 12.00 - 12.30 12.30 - 13.00 |
K. Chaloner ( Design of population studies of
HIV dynamics (abstract, slides) C. Bazzoli1, S.
Retout1,2 and F. Mentre1,2 (1. INSERM, 2. AP-HP, Hopital Bichat) Population design in nonlinear
mixed effects multiple responses models: extension of PFIM and evaluation by
simulation with NONMEM and MONOLIX (abstract,
slides) M. Patan1, B. Bogacka2 (1. Construction of population designs for nonlinear models
via selective random search (abstract,
slides) |
13.00 - 14.00 |
Lunch |
Practical Issues 14.00 - 14.15 14.15 - 14.30 14.30 - 14.45 14.45 - 15.00 15.00 - 15.15 |
P. Johnson (Pfizer) Optimal dose & sample-size
selection for dose-response studies (abstract,
slides) K. Ogungbenro, M. Chenel and L. Aarons (University of Manchester) Optimal design for drug-drug
interaction study using PopDes - application to SX and MDZ (abstract, slides) G. Hegarty1, J. McGree2, S.Duffull1
(1. University of Otago, 2. University of Queensland) Rescuing a population PK study and
assessing its performance for covariate identification (abstract, slides) I. Gueorguieva and K. Jackson (Lilly Research
Centre) Prospective application of a
multivariate population optimal design to determine parent and metabolite
pharmacokinetic sampling times in a Phase II study (abstract, slides) G. Graham (Pfizer) Examples of the application of optimum design to nonlinear
mixed effects models at Pfizer (abstract,
slides) |
15.15 - 15.45 |
Tea/coffee |
Software Session 15.45 - 16.10 16.10 - 16.35 16.35 - 17.00 17.00
- 17.25 17.25 - 17.50 |
S. Duffull (University of Otago) Walking with WinPOPT (abstract, slides) S.
Retout1, 2, C. Bazzoli1, E. Comets1,
H. Le Nagard1, F. Mentre1, 2 (1. INSERM, 2. AP-HP, Hopital Bichat) Population designs evaluation and
optimisation in R: the PFIM function and its new features (abstract, slides) K. Ogungbenro, I. Gueorguieva, G. Graham and L. Aarons (University of
Manchester) PopDes - an optimal experimental
design program for individual and population uniresponse and multiresponse
PKPD models (abstract, slides) A. Hooker (Uppsala University) Population optimal experimental design using PopED (Population optimal Experimental Design) (abstract, slides)
S. Leonov (GlaxoSmithKline) PkStaMp - optimal designs for
compartment models (abstract, slides) |
17.50 - 18.00 |
Break |
Discussion 18.00
- 18.30 |
Lead by France Mentre (INSERM and AP-HP, Hopital
Bichat) |
~ PODE ~ |